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From the Desk of the Vice Chancellor

Greetings!

As the Vice Chancellor of this premier university, I am extremely pleased to share this space to converse with all of you. The University of Madras is a post- sesquicentennial institution which has forged a glorious path for itself and has been the site for significant scientific discoveries as well as the beacon for national and regional societal transformation. It has successfully managed to hold aloft its tradition even while keeping up with the emerging trends. One reason for this is the way in which the university has kept alive its interactions with all the stakeholders.

The COVID 19 pandemic has introduced a ‘new normal’ and its impact is felt in the workings of the university as well. The students have been attending the lectures online. While online learning has the advantage of being anytime and anywhere, it has taken away the peer group interaction and peer learning which are integral aspects of the university experience. We look forward to welcoming you to the campus very soon. Meanwhile, our faculty and administration will continue to bring the best to the virtual classrooms. As students, you need to view the restrictions posed by the pandemic as a temporary deterrent. Your focus should be to gain the competencies to conduct application oriented research in order to evolve as useful citizens of our society.

Our university boasts of faculty with a high degree of knowledge and commitment to offer the best in teaching and research. Given the context of the pandemic, we need to redefine our teaching-learning processes to offer the best pedagogic experience to our students. Similarly, the post-pandemic era demands that we hone the employment potential and entrepreneurial capacity of our learners. This necessitates that we focus on sponsored research in cutting edge areas.

Our administrative staff have been the backbone of the university. While we move towards a transparent and complete e-governance model, we need more support from you. When the teaching-learning process at our university – from admission to certification -- is moving into the digital era, your skills and competencies need to keep pace.

At our university, we are gearing up for the final round of NAAC re-accreditation. This has offered us an opportunity to assess our Strengths, Weaknesses, Opportunities and Challenges. Further, it has made us more determined to reiterate our quality benchmarks in teaching, research and extension activities. We are aware of this responsibility and fully prepared for it because, our university has always encouraged individual thinking within the established frameworks. This is echoed in the words of Tim Burners Lee, who initiated the World Wide Web: “We are forming cells within a global brain and we are excited that we might start to think collectively. What becomes of us still hangs crucially on how we think individually.” Let us unite to make the educational experience at the University of Madras a synergy of the best minds and best thoughts.

Prof.Dr.S.Gowri

Vice-Chancellor
University of Madras

Dr.V.RajakannanM.Sc., B.Ed., M.Phil., Ph.D., FASCh

Assistant professor
Department of Crystallography and Biophysics
0

Awards

45

Publications

31

Seminars / Conference

3

Projects

1

Ph.D Awarded

3

Ph.D Present

Publications

Articles (Total Articles: 43)

# Title Author Publisher Volume Year Page(s)
1  Insilico Studies of Molecular Property and Bioactivity of Organic Crystalline Compounds using Molinspiration,    M. Suganya, MadhukarHemamalini, S. JoseKavitha, Venkatachalam Rajakannan International Research Journal of Engineering and Technology, Feb 2020 Volume: 07 Issue: 02
2 Design and synthesis of imidazole-based zinc binding groups as novel small molecule inhibitors targeting Histone deacetylase enzymes in lung cancer. Saravanan Kandasamy, Prabhu Subramani, Selvi Subramani, John marshal Jayaraj, Gunasekaran Prasanth, Kannupal Srinivasan, Karthikeyan Muthusamy, Venkatachalam Rajakannan, Ravikumar Vilwanathan Journal of Molecular Structure Elsevier 2020 128177
3 Synthesis, crystal structure, Hirshfeld surface analysis, In-Silico assessment of druggability and molecular docking studies of Schiff base compound. Necmi Dege, Alev Sema Ayd?n, Erbil A?ar, Sevgi Kans?z, Savaridasan JoseKavitha, Kasthuri BalaSubramani, Madhukar Hemamalini, Venkatachalam Rajakannan Chemical Data Collections Elsevier, Volume 25 2020
4  2-Amino-6-chloropyridine–glutaric acid (1/1)2-Amino-6-chloropyridine–glutaric acid (1/1)2-Amino-6-chloropyridine–glutaric acid (1/1)2-Amino-6-chloropyridine–glutaric acid (1/1). . 4.  Manickam, R. & Prabhaharan, M. & Jagadeesan, G. & Rajakannan, Venkatachalam & Srinivasan, G IUCrData IUCR 2019
5 2-Amino-6-chloropyridinium 3-carboxy-4-hydroxybenzenesulfonate2-Amino-6-chloropyridinium 3-carboxy-4-hydroxybenzenesulfonate 2-Amino-6-chloropyridinium 3-carboxy-4-hydroxybenzenesulfonate2-Amino-6-chloropyridinium 3-carboxy-4-hydroxybenzenesulfonate. Manickam, R. & Rajakannan, Venkatachalam & Prabhaharan, M. & Srinivasan, G. IUCrData IUCR 2019
6 Structural investigation of (2E)-2-(ethoxycarbonyl)-3-[(4-methoxyphenyl)amino]prop-2-enoic acid: X-ray crystal structure, spectroscopy and DFT. Perumal, Venkatesan & Rajakannan, Venkatachalam & Natarajan Sathiyamoorthy, Venkataramanan & Andivelu, Ilangovan & Sundius, Tom & Thamotharan, s Journal of Molecular Structure Elsevier 2016
7 Structure of C-Terminal Domain of the Multifunctional ICP27 Protein from Herpes Simplex Virus-1. Journal of virology. 89. 10.1128/JVI.00441-15. Patel, Vidhi & Dahlroth, Sue-Li & Rajakannan, Venkatachalam & Ho, Hai & Cornvik, Tobias & Nordlund, Pär. Journal of Virology Elsevier, Volume 89 2015
8  Crystal structure of 3-amino-1-propylpyridinium bromide. Perumal, Venkatesan & Rajakannan, Venkatachalam & Thamotharan, s. Acta crystallographica. Section E Structure reports online. 70. 2014 580-3
9 The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor.  Hew, Kelly & Dahlroth, Sue-Li & Rajakannan, Venkatachalam & Nasertorabi, Fariborz & Lim, Bee & Cornvik, Tobias & Nordlund, Pär. Nucleic acids research. 41 2013
10 2-Amino-5-chloropyrimidin-1-ium hydrogen maleate. Fun, Hoong-Kun & Hemamalini, Madhukar & Rajakannan, Venkatachalam. Acta crystallographica. Section E Structure reports online, 68 2012
11 Structural Basis of Cooperativity in Human UDP-Glucose Dehydrogenase Rajakannan, Venkatachalam & Lee, Hui-Sun & Chong, Seon-Ha & Ryu, Han-Bong & Bae, Ji-Young & Whang, Eun-Young & Huh, Jae-Wan & Cho, Sung-Woo & Kang, Lin-Woo & Choe, Han & Robinson, Robert. PloS one 6 2011
12 4-Aminopyridinium 4-carboxybutanoate.  Hoong-Kun, Fun & Madhukar, Hemamalini & Rajakannan, Venkatachalam. Acta Crystallographica Section E 66 2010
13  4-Aminopyridinium 2-hydroxybenzoate. Acta Crystallographica Section E. Hoong-Kun, Fun & Madhukar, Hemamalini & Rajakannan, Venkatachalam. Acta Crystallographica Section E 66 2010
14  Purification, crystallization and preliminary X-ray diffraction analysis of the HMG domain of Sox17 in complex with DNA. Ng, C.K., Palasingam, P., Venkatachalam, R., Baburajendran, N., Cheng, J.C., Jauch, R., & Kolatkar, P.R. Structural biology and crystallization communications Acta crystallographica. Section F 2008 1184-7
15 Ab Initio Structure Determination of the Triple Mutant (K53,56,121M) of Bovine Pancreatic Phospholipase A(2) at Atomic and High Resolution Using ACORN. D. Velmurugan, V. Rajakannan, D. Gayathri, S. Banumathi, T. Yamane, Z. Dauter, M. Dauter and K. Sekar. 2006
16 Atomic resolution (0.97 A) structure of the triple mutant (K53,56,121M) of bovine pancreatic phospholipase A2.” , Structural biology and  (2004):  Kanagaraj Sekar, Venkatachalam Rajakannan, Dr Gayathri, D. Velmurugan, M-J Poi, Miroslawa Dauter, Zbigniew Dauter, M. Tsai. Acta crystallographica. Section F crystallization communications 61 Pt 1 2004 3-7
17  New copper(II) complexes of 2-hydroxyacetophenone N(4)-substituted thiosemicarbazones and polypyridyl co-ligands: Structural, electrochemical and antimicrobial studies. John, Rohith & Sreekanth, A. & Rajakannan, Venkatachalam & Ajith, T. & Kurup, M R. 23 Polyhedron 2004 2549-2559
18 A redetermination of the structure of the triple mutant (K53,56,120M) of phospholipase A2 at 1.6 A resolution using sulfur-SAS at 1.54 A wavelength.  Sekar, K., Rajakannan, V., Velmurugan, D., Yamane, T., Thirumurugan, R., Dauter, M., & Dauter, Z Acta crystallographica. Section D, Biological crystallography 60 2004 1586-90
19 Crystal structure analysis of 5-amino-7-(pyrrolidin-1-yl)-2,4,4-trimethyl-1,4-dihydro-1,6-naphthyridine-8-carbonitrile. Selvanayagam, Sivashanmugam & Rajakannan, Venkatachalam & Rao, S. & Raj, Siva & Fun, H. & Raghukumar, V. & Velmurugan, Devadasan. Crystal Research and Technology CRYST RES TECH. 39 2004 172-178
20 The use of ACORN in solving a 39.5 kDa macromolecule with 1.9 A resolution laboratory source data.  2004 Jul 1;:. doi: 10.1107/S0909049504011185. Epub 2004 Jun 23. Rajakannan V, Selvanayagam S, Yamane T, Shirai T, Kobayashi T, Ito S, Velmurugan D. J Synchrotron Radiat. 11(Pt 4) 2004 358-62
21 Applications of ACORN to data at 1.45 Å resolution. Rajakannan, Venkatachalam & Yamane, T & Shirai, Tsusyoshi & Kobayashi, Tohru & Ito, Susumu & Velmurugan, Devadasan. Journal of Synchrotron Radiation 11 2004 64-67
22 6,22-Dioxaparazyl­enyl 2,10,18,26-tetra­thia-33,35 di­azapenta­cyclo[27.3.1.14,8.112,16.120,24]hexatriconta-4,6,8(36),12,14,16(35),20,22,24(34),28,30,32-dodecaene. Bhaskaran, Sundari & Selvanayagam, Sivashanmugam & Rajakannan, Venkatachalam & Velmurugan, Devadasan & Narasingarao, S. & Dhanasekaran, M. & Rajakumar, P. & Kim, Moon?Jib. Acta Crystallographica Section E. 59 2003
23 30,31-Di­methyl-3,26-dioxa-11,18-di­aza­penta­cyclo­[26.4.0.04,9.012,17.020,25]­dotriconta-1(32),4,6,8,12,14,16,20,22,24,28,30-dodecaene-10,19-dione.  Bhaskaran, Sundari & Selvanayagam, Sivashanmugam & Rajakannan, Venkatachalam & Velmurugan, Devadasan & Ravikumar, Kakara & Abdul Rasheed, Mohammed & Rajakumar, P. Acta Crystallographica Section E. 59. Acta Crystallographica Section E. 59. 2003
24 34,35-Di­methyl-13,20-dioxa-10,23-di­aza-3,30-di­thia­penta­cyclo­[30.4.0.04,9.014,19.024,29]­hexatriconta-1(36),4,6,8,14,16,18,24,26,28,32,34-do­decane-11,22-dione. Bhaskaran, Sundari & Selvanayagam, Sivashanmugam & Rajakannan, Venkatachalam & Velmurugan, Devadasan & Ravikumar, Kakara & Abdul Rasheed, Mohammed & Rajakumar, P Acta Crystallographica Section E. 59 2003
25  4-Acetamido-2-methoxy-5-[3-(phenylsulfanyl) indole-2-carbonyl] benzoic Acid. Rajakannan, V., Selvanayagam, S., Yogavel, M., Govindasamy, L., Velmurugan, D., Shanmuga Sundara Raj, S., Fun, H.-K. & Srinivasan, P. C. Acta Cryst. E59 Acta Cryst. E59 2003
26 3-Phenyl-4a,5-di­hydro-1,2,4-triazolo­[3,4-b][1,3]­benzo­thia­zine. Aravindan, P. & Rajakannan, Venkatachalam & Manickam, Yogavel & Velmurugan, Devadasan & Suh, Il?Hawn & Senthilvelan, A. Acta Crystallographica Section E. Acta Crystallographica Section E. 59. 2003
27 2-Hydroxy-4,4-di­methyl-N-(4-methyl­phenyl-6-oxo­cyclo­hexanyl­acetamide. Selvanayagam, Sivashanmugam & Manickam, Yogavel & Rajakannan, Venkatachalam & Velmurugan, Devadasan & Raj, Siva & Fun, Hoong?Kun. Acta Crystallographica Section E. Acta Crystallographica Section E. 59. 2003
28  Crystal structure of 3-hydroxy methyl 4,6-dimethoxy-9-phenylsulfonyl-carbazole. Govindasamy (Govinda), La & Rajakannan, Venkatachalam & Velmurugan, Devadasan & Mohanakrishnan, Arasambattu & Srinivasan, P.. Crystal Research and Technology CRYST RES TECH. 39 2003
29 Govind, M. & Govindaraj, J. & Rajakannan, Venkatachalam & Velmurugan, Devadasan & Kim, Moon & Srinivasan, P. & Kannadasan, S Acta Crystallographica Section E-structure Reports Online ACTA CRYSTALLOGR E-STRUCT REP. 2003 2-Bromo-N-[3-bromo-1-(phenylsulfonyl)indol-2-ylmethyl]-4-methylaniline.
30 5-Amino-4-(4-di­methyl­amino­phenyl)-2-(4-methoxy­phenyl)-7-(pyrrolidin-1-yl)-1,6-naphthyridine-8-carbo­nitrile. Bhaskaran, Sundari & Manickam, Yogavel & Rajakannan, Venkatachalam & Krishna, Raghuram & Velmurugan, Devadasan & Raghukumar, V.. Acta Crystallographica Section E. Acta Crystallographica Section E. 59. 2003
31  Observation of Additional Calcium Ion in the Crystal Structure of the Triple Mutant K56,120,121M of Bovine Pancreatic Phospholipase A2.  . 10.1016/S0022-2836(02)01132-4. Manickam, Yogavel & Rajakannan, Venkatachalam & Krishna, Raghuram & Velmurugan, Devadasan & Raghukumar, V. Journal of molecular biology Journal of molecular biology. 324. 2002 755-62
32 2-Methoxy­benz­aldehyde thio­semicarbazone. Selvanayagam, Sivashanmugam & Manickam, Yogavel & Rajakannan, Venkatachalam & Velmurugan, Devadasan & Raj, Siva & Fun, Hoong?Kun. Acta Crystallographica Section E Acta Crystallographica Section E. 58 2002
33 2,6Bis( N,N ′-benzotriazol-1-ylmethyl)pyridine. Selvanayagam, Sivashanmugam & Rajakannan, Venkatachalam & Velmurugan, Devadasan & Dhanasekaran, M. & Rajakumar, P. & Moon, Jib-Kim. Acta Crystallographica Section E-structure Reports Online ACTA CRYSTALLOGR E-STRUCT REP. 58. 2002
34 2-Bromo-N-[3-bromo-N-(phenyl­sulfonyl)­indol-2-yl­methyl]­aniline.  10.1107/S1600536802018457. Govind, M. & Govindaraj, J. & Rajakannan, Venkatachalam & Velmurugan, Devadasan & Kim, Moon?Jib & Srinivasan, P. & Kannadasan, S. Acta Crystallographica Section E. Acta Crystallographica Section E. 58. 2002
35 2,6-Bis(N,N′-benzotriazol-1-yl­methyl)­pyridine.  Selvanayagam, Sivashanmugam & Rajakannan, Venkatachalam & Velmurugan, Devadasan & Dhanasekaran, M. & Rajakumar, P. & Moon, Jib?Kim. Acta Crystallographica Section E. Acta Crystallographica Section E. 58 2002
36 Crystal Structure of Dimeric Cu(II) Complex {μ,μ'-acetato O,O bis [N-salicylidene-2-amino-pyridine-methanolato N,N,O]} : perchlorate. Govindasamy (Govinda), La & Rajakannan, Venkatachalam & Velmurugan, Devadasan & Raj, Siva & Rajendran, T. & Venkatesan, R. & Srinivasan, R. & Fun, H.. Crystal Research and Technology. Crystal Research and Technology. 37 2002
37 Structural Studies on Three Plant Diterpenoids from Leonotis nepetaefolia.  Govindasamy (Govinda), La & Rajakannan, Venkatachalam & Velmurugan, Devadasan & Banumathi, S. & Vasanth, S. Crystal Research and Technology CRYST RES TECH. 37. 2002
38 4-Chloro-2-(4-chloro­phenyl)-1-formyl-1,2-di­hydro­quinoline.  Thinagar, S. & Velmurugan, Devadasan & Rajakannan, Venkatachalam & Suh, Il?Hwan & Akila, S. Acta Crystallographica Section E. Acta Crystallographica Section E. 2002
39 Spiro­[5-carbo­methoxy-2-(4-methoxy­phenyl)-4-(4-methyl­phenyl)­pyrrolidine-3,3′-chroman-4′-one].  Nissa, M. & Rajakannan, Venkatachalam & Kim, Moon?Jib & Subramaniyan, G. & Raghava, Raghunathan & Velmurugan, Devadasan. Acta Crystallographica Section E. Acta Crystallographica Section E. 2002
40 2-Bromo- N -[3-bromo- N -(phenylsulfonyl)indol-2-ylmethyl]aniline. Govind, M. & Govindaraj, J. & Rajakannan, Venkatachalam & Velmurugan, Devadasan & Kim, Moon-Jib & Srinivasan, P. & Kannadasan, S. Acta Crystallographica Section E-structure Reports Online ACTA CRYSTALLOGR E-STRUCT REP. 58. 2002
41 Spiro­[2-carbo­methoxy-5-(4-methoxy­phenyl)-3-phenyl­pyrrolidine-4,3′-chroman-4′-one].   Nissa, M. & Rajakannan, Venkatachalam & Kim, Moon?Jib & Velmurugan, Devadasan. Acta Crystallographica Section E. Acta Crystallographica Section E. 57. 2001
42   A unique example of a pseudo-peptide containing noncoded amino acids self-assembling into a supramolecular β-sheet-like structure in crystals.  Maji, Samir & Halder, Debesh & Velmurugan, Devadasan & Rajakannan, Venkatachalam & Banerjee, Arindam. Letters in Peptide Science. Letters in Peptide Science. 8. 2001 61-67
43 2-Amino-6-chloropyridinium 3-carboxy-4-hydroxybenzenesulfonate2-Amino-6-chloropyridinium 3-carboxy-4-hydroxybenzenesulfonate 2-Amino-6-chloropyridinium 3-carboxy-4-hydroxybenzenesulfonate2-Amino-6-chloropyridinium 3-carboxy-4-hydroxybenzenesulfonate. Chakkarapani, N., Murugan, S., Ibrahim, A. R., Kavitha, S. J., Hemamalini, M. & Rajakannan, V. IUCR IUCR 2020
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