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From the Desk of the Vice Chancellor

Greetings!

As the Vice Chancellor of this premier university, I am extremely pleased to share this space to converse with all of you. The University of Madras is a post- sesquicentennial institution which has forged a glorious path for itself and has been the site for significant scientific discoveries as well as the beacon for national and regional societal transformation. It has successfully managed to hold aloft its tradition even while keeping up with the emerging trends. One reason for this is the way in which the university has kept alive its interactions with all the stakeholders.

The COVID 19 pandemic has introduced a ‘new normal’ and its impact is felt in the workings of the university as well. The students have been attending the lectures online. While online learning has the advantage of being anytime and anywhere, it has taken away the peer group interaction and peer learning which are integral aspects of the university experience. We look forward to welcoming you to the campus very soon. Meanwhile, our faculty and administration will continue to bring the best to the virtual classrooms. As students, you need to view the restrictions posed by the pandemic as a temporary deterrent. Your focus should be to gain the competencies to conduct application oriented research in order to evolve as useful citizens of our society.

Our university boasts of faculty with a high degree of knowledge and commitment to offer the best in teaching and research. Given the context of the pandemic, we need to redefine our teaching-learning processes to offer the best pedagogic experience to our students. Similarly, the post-pandemic era demands that we hone the employment potential and entrepreneurial capacity of our learners. This necessitates that we focus on sponsored research in cutting edge areas.

Our administrative staff have been the backbone of the university. While we move towards a transparent and complete e-governance model, we need more support from you. When the teaching-learning process at our university – from admission to certification -- is moving into the digital era, your skills and competencies need to keep pace.

At our university, we are gearing up for the final round of NAAC re-accreditation. This has offered us an opportunity to assess our Strengths, Weaknesses, Opportunities and Challenges. Further, it has made us more determined to reiterate our quality benchmarks in teaching, research and extension activities. We are aware of this responsibility and fully prepared for it because, our university has always encouraged individual thinking within the established frameworks. This is echoed in the words of Tim Burners Lee, who initiated the World Wide Web: “We are forming cells within a global brain and we are excited that we might start to think collectively. What becomes of us still hangs crucially on how we think individually.” Let us unite to make the educational experience at the University of Madras a synergy of the best minds and best thoughts.

Prof.Dr.S.Gowri

Vice-Chancellor
University of Madras

Dr. M. RaviPh.D

Assistant Professor
Department of Biochemistry
0

Awards

26

Publications

27

Seminars / Conference

5

Projects

0

Ph.D Awarded

3

Ph.D Present

Seminar / Conference

National Seminar Participated

S.No Description Year Held
1

 Ravi Manoharan and Hyunjung, H.A.Cationic-liposome-mediated 14-3-3 gene therapy enhances the MPK38-mediated apoptosis effect in breast and lung cancer.  Chennai Nanogathering 2017, University of Madras, Chennai,Tamil nadu, 7-8 February, 2017

2017
2

Lavanya Ponnusamy and Ravi Manoharan. Combine effect of Emodin and Berberine inhibit cell proliferation and induce cell cycle arrest in human breast cancer cells via mTOR signaling pathway.  National conference on Basic and Applied Biological sciences, Bharathiar university, Coimbatore, Tamil Nadu, 10-11 October, 2018

2018
3

Lavanya Ponnusamy, Sathan Raj Natarajan, and  Ravi Manoharan. Berberine induces cell cycle arrest and apoptosis of breast cancer cells through regulation of AMPK and SIK kinases. National Conference on “Biochemical and Molecular basis of Cancer”, Department of Biochemistry, Meenakshi Medical College & Research Institute, Enathur, Kanchipuram, Tamil nadu.19th October, 2019

2019

International Seminar Participated

S.No Description Year Held
1

Haiyoung Jung, Hyun-A Seong, Ravi Manoharan, and Hyunjung Ha.  Serine-threonine kinase receptor-associated protein (STRAP) negatively regulates apoptosis signal-regulating kinase 1 activity. “Life’s Molecular Interactions” 34th FEBS Congress,  Prague, Czech Republic,4-8 July 2009

2009
2

Hyun-A Seong, Ravi Manoharan, and Hyunjung Ha. Murine protein serine/threonine kinase 38 (MPK38) regulates TGF-beta-mediated signaling through direct phosphorylation of Smad proteins. 14th International congress of immunology,  Kobe, Japan, 23-27August 2010.

2010
3

Hyun-A Seong, Ravi Manoharan, and Hyunjung Ha. Negative regulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) signaling by murine protein serine/threonine kinase 38 (MPK38). 8th AACR-JCA conference, Waikoloa, USA,5-9 February 2010

2010
4

Ravi Manoharan, Hyun-A Seong, and Hyunjung Ha. Suppression of Murine Protein Serine/Threonine Kinase 38 (MPK38) activity by thioredoxin. “Biochemistry for Tomorrow’s medicine” 36th FEBS congress,  Torino, Italy, 25-30June 2011

2011
5

Hyun-A Seong, Ravi Manoharan, and Hyunjung Ha, Serine-threonine kinase receptor-associated protein (STRAP) activates B-myb function through direct interaction. “Experimental biology 2011” ASBMB meeting,  Washington, DC, USA,9-13April 2011

2011
6

Ravi Manoharan, Hyun-A Seong, and Hyunjung Ha.. Suppression of Murine Protein Serine/Threonine Kinase 38 (MPK38) activity by Thioredoxin. The 12th Daejeon and Chungcheong coalition postgraduate student conference, organized by KSMCB,  Daejeon, South Korea, 18-19August 2011

2011
7

Hyun-A Seong, Ravi Manoharan, Jang H-J, Kim S, and Hyunjung Ha. Critical role of murine protein serine/threonine kinase 38 (MPK38)-mediated phosphorylation of serine-threonine kinase receptor-associated protein (STRAP) at Ser188 in STRAP-mediated cell death. “From single molecules to systems biology” 22nd IUBMB and 37th FEBS congress,  Sevilla, Spain, 4-9 September, 2012

2012
8

Ravi Manoharan, Hyun-A Seong, and Hyunjung Ha. 14-3-3 positively regulates murine protein serine-threonine kinase 38 in a phosphorylation-dependent manner. “Mechanisms in Biology” 38th FEBS Congress, Saint Petersburg, Russia, 6-11, July, 2013

2013
9

Hyun-A Seong, Ravi Manoharan, and Hyunjung Ha, Smad proteins differentially regulate the activity of murine protein serine-threonine kinase 38 (MPK38). FEBS-EMBO 2014 Conference, Paris, France,  30August-4 September 2014.

2014
10

 

Ravi Manoharan, Hyun-A Seong, and Hyunjung Ha. Regulation of p53-dependent metabolic functions by zinc finger protein ZPR9. 40th FEBS Congress, Berlin, Germany.

2015
11

Hyun-A Seong, Ravi Manoharan, and Hyunjung Ha. Coordinate regulation of ASK1/TGF-β signaling contributes to improved glucose and lipid metabolism in mice. Expriment biology 2015, Boston, USA,28 March-1April 2015

2015
12

Hyun-A Seong, Ravi Manoharan, and Hyunjung Ha. AMPK-related kinase MPK38/MELK potentiates p21-mediated apoptosis, cell cycle arrest, and inhibition of adipocyte differentiation via Thr55 phosphorylation. Experiment Biology CHICAGO 2017, Chicago, USA

2017
13

Ravi Manoharan, Hyun-A Seong, and Hyunjung Ha. Daxx contributes to an anti obesity by activating an AMPK-related serine/threonine kinase MPK38/MELK in diet-induced obese mice. 18th International Congress of Endocrinology, Cape Town, South Africa.

2018
14

Lavanya P, and Ravi Manoharan. Combined treatment of Emodin and Berberine attenuate cell proliferationand promote cell cycle arrest through inhibition of SIK3-mediated mTOR/AKT pathway inbreast cancer cells. 8th Annual Conference of Indian Academy of Biomedical sciences. CSIR-NIIST, Trivandrum, kerala.

2019
15

Lavanya Ponnusamy, Jaithanya Y.M, and  Ravi Manoharan.  MARK2 potentiate mTOR/HIF-1α/p53 mediated aerobic glycolysis and cell growth by preventing cell death in breast cancer cells. 3rd International Conference on Genome Biology (ICGB-3) organized by School of Biological Sciences · Madurai Kamaraj University, Madurai,  28th February- 2nd March,2022.

2022
16

 Sathan Raj Natarajan, and  Ravi Manoharan.. MARK2/4 promotes aerobic glycolysis and cell growth in non-small cell lung carcinoma through the AMPK/mTOR/HIF-1α signaling pathway. 3rd International Conference on Genome Biology (ICGB-3) organized by School of Biological Sciences · Madurai Kamaraj University, Madurai,  28th February- 2nd March,2022.

2022
17

 Sathan Raj Natarajan, and  Ravi Manoharan. Fisetin abrogates cell growth and metastasis and facilitates apoptosis through the inactivation of MARK isoforms in non-small cell lung carcinoma. International conference on Biotechnology and information technology in Drug Discovery and Development (ICBITDD-2022) by the Department of Biochemistry and Biotechnology, Annamalai University, Chidhambaram,  25th – 26th June 2022.

2022
18

Lavanya Ponnusamy,  and  Ravi Manoharan. Salt-Inducible Kinase (SIK3) facilitates AKT1/mTOR-mediated aerobic glycolysis, cell growth, and metastasis in breast cancer cells. International conference on Biotechnology and information technology in Drug Discovery and Development (ICBITDD-2022) by the Department of Biochemistry and Biotechnology, Annamalai University, Chidhambaram,   25th – 26th June 2022.

2022
19

Jaithanya Y.M and Ravi Manoharan.  Ellagic acid inhibits cervical cancer growth and facilitates apoptosis through stimulating SIK1 activity. International conference on Biotechnology and information technology in Drug Discovery and Development (ICBITDD-2022) by the Department of Biochemistry and Biotechnology, Annamalai University, Chidhambaram, 25th – 26th June 2022.

2022
20

Acily Skadon.W., and Ravi Manoharan. NUAK1/2 isoforms facilitates glucose metabolic reprogramming mediated breast cancer cell growth and metastasis. International conference on cancer biology: Molecular mechanisms, Genomics and Novel therapeutics (iccb-23) by the Department of Biotechnology, IIT -Madras, 14 – 16th September 2023

2023
21

Moorthy Babu, J.Y., and  Ravi Manoharan.  SIK1/2 impaired aerobic glycolysis, cell growth, and metastasis in NSCLC cells. International conference on cancer biology: Molecular mechanisms, Genomics and Novel therapeutics (iccb-23) by the Department of Biotechnology, IIT -Madras,14 – 16th September 2023.

2023
22

 

Acily Skadon. W, Lavanya. P and Ravi Manoharan. NUAK1/2 facilitates mTOR/c-MYC mediated breast cancer cell proliferation and metastasis. International conference on Molecular Medicine and Therapeutics (ICMT-2023) by the Department of Biochemistry and Biotechnology, Annamalai University, Chidhambaram, 07 – 09 January 2023.

2023
23

Jaithanya Y.M and Ravi Manoharan. NUAK1/2 facilitates aerobic glycolysis, cell growth, and metastasis in NSCLC cells through regulating mTOR/p53 signaling pathways. International conference on Molecular Medicine and Therapeutics (ICMT-2023) by the Department of Biochemistry and Biotechnology, Annamalai University, Chidhambaram, 07 – 09 January 2023

2023
24

  Acily Skadon.W., and Manoharan, R. NUAK isoforms facilitate colon cancer cell growth and metastasis via reprogramming glucose metabolism. International conference on Frontier research in life sciences: Molecular mechanisms, Genomics and Novel therapeutics (ICFRLS-2025) by the Department of Zoology, University of Madras, Chennai, 

23rd
// FLASH NEWS //
  • University of Madras attains category - 1 status from UGC |  NIRF Ranking - Ranked 39 in University Category 2024 |  University of Madras has been graded A++ in the NAAC Assessment

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