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From the Desk of the Vice Chancellor

Greetings!

As the Vice Chancellor of this premier university, I am extremely pleased to share this space to converse with all of you. The University of Madras is a post- sesquicentennial institution which has forged a glorious path for itself and has been the site for significant scientific discoveries as well as the beacon for national and regional societal transformation. It has successfully managed to hold aloft its tradition even while keeping up with the emerging trends. One reason for this is the way in which the university has kept alive its interactions with all the stakeholders.

The COVID 19 pandemic has introduced a ‘new normal’ and its impact is felt in the workings of the university as well. The students have been attending the lectures online. While online learning has the advantage of being anytime and anywhere, it has taken away the peer group interaction and peer learning which are integral aspects of the university experience. We look forward to welcoming you to the campus very soon. Meanwhile, our faculty and administration will continue to bring the best to the virtual classrooms. As students, you need to view the restrictions posed by the pandemic as a temporary deterrent. Your focus should be to gain the competencies to conduct application oriented research in order to evolve as useful citizens of our society.

Our university boasts of faculty with a high degree of knowledge and commitment to offer the best in teaching and research. Given the context of the pandemic, we need to redefine our teaching-learning processes to offer the best pedagogic experience to our students. Similarly, the post-pandemic era demands that we hone the employment potential and entrepreneurial capacity of our learners. This necessitates that we focus on sponsored research in cutting edge areas.

Our administrative staff have been the backbone of the university. While we move towards a transparent and complete e-governance model, we need more support from you. When the teaching-learning process at our university – from admission to certification -- is moving into the digital era, your skills and competencies need to keep pace.

At our university, we are gearing up for the final round of NAAC re-accreditation. This has offered us an opportunity to assess our Strengths, Weaknesses, Opportunities and Challenges. Further, it has made us more determined to reiterate our quality benchmarks in teaching, research and extension activities. We are aware of this responsibility and fully prepared for it because, our university has always encouraged individual thinking within the established frameworks. This is echoed in the words of Tim Burners Lee, who initiated the World Wide Web: “We are forming cells within a global brain and we are excited that we might start to think collectively. What becomes of us still hangs crucially on how we think individually.” Let us unite to make the educational experience at the University of Madras a synergy of the best minds and best thoughts.

Prof.Dr.S.Gowri

Vice-Chancellor
University of Madras

Dr.V.AravindhanM.Sc., M.Phil., Ph.D.

Assistant professor
Department of Genetics
2

Awards

42

Publications

8

Seminars / Conference

6

Projects

1

Ph.D Awarded

3

Ph.D Present

Publications

Articles (Total Articles: 21)

# Title Author Publisher Volume Year Page(s)
1   Serum levels of novel anti-inflammatory cytokine Interleukin-38 in diabetes patients infected with latent tuberculosis (DM-LTB-3). Aravindhan V*, Bobhate A, Sathishkumar K, Viswanathan V. J Diabetes Complications. 36(3) 2022 108133
2 Emerging neuroprotective interventions in periventricular leukomalacia: A systematic review of preclinical studies. Abiramalatha T, Ramaswamy VV, Ponnala AK, Kallem VR, Murkunde YV, Punnoose AM, Vivekanandhan A, Pullattayil AK, Amboiram P. 31(3) Expert Opin Investig Drugs. 2022 305-330
3    RETRA induces necroptosis in cervical cancer cells through RIPK1, RIPK3, MLKL and increased ROS production. Mohanty S, Yadav P, Lakshminarayanan H, Sharma P, Vivekanandhan A, Karunagaran D. Epub ahead of print Eur J Pharmacol. 2022 Epub ahead of print
4 Unique Reciprocal Association seen between Latent Tuberculosis Infection and Diabetes is due to Immunoendocrine Modulation (DM-LTB-1). 1. Aravindhan V.*, Bobhate A., Sathishkumar K., Patil A., Kumpatla S. and Viswanathan V. Front. Microbiol. 13:884374. 2022 1-11
5 Decreased leukocyte exhaustion is associated with decreased IFN-β and increased α-defensin-1 levels in type-2 diabetes Shruthi S., Sibi J.M, Mohan V., Babu S., Nirmaladevi V., Aravindhan V*. Cytokine 156:155918 2022 1-12
6  (2022) Modulatory effect of filarial infection on the systemic hormone levels in subjects with metabolic syndrome (DM-LF5).   doi: 10.3389/fendo.2022.1011942 Sibi JM, Mohan V, Deepa M, Babu S and Aravindhan V Front. Endocrinol. 13:1011942. 2022 1-8
7     Augmented Innate and Adaptive Immune Responses Under Conditions of Diabetes–Filariasis Comorbidity. Sibi JM, Mohan V, Munisankar S, Babu S and Aravindhan V*. Front. Immunol 12:716515 2021 1-12
8          Anti-inflammatory cytokines IL-27, IL-10, IL-1Ra and TGF-β in subjects with increasing grades of glucose intolerence (DM-LTB-2)     Bobhate A., Viswanathan V., Aravindhan V Cytokine 2021
9   The Strange Case of BCG and COVID-19: The Verdict Is Still up in the Air. Gopalaswamy R., Ganesan N., Velmurugan K., Aravindhan V. and Subbian S. Vaccines. 8 (4) 2020 612
10        In silico identification and wet lab validation of novel cryptic B cell epitopes in ZnT8 zinc transporter autoantigen. Int J Biol Macromol. 2019 Apr 15;127:657-664. Shruthi S, Mohan V, RaoMaradana M, Aravindhan V Int J Biol Macromol 127 2019 657-664
11 Single nucleotide polymorphisms in cytokine/chemokine genes are associated with severe infection, ulcer grade and amputation in diabetic foot ulcer Viswanathan V*, Dhamodharan U, Srinivasan V, Rajaram R, Aravindhan V*. International Journal of Biological Macromolecules 118 2018 1995-2000
12 Serum levels of chemokines IP-10, IL-8 and SDF-1 serve as good biomarkers for diabetes-tuberculosis nexus   Aravindhan V, Kevinkumar V, Dhamodharan U, Viswanathan V J Diabetes Complications Sep;32(9) 2018 857-862
13 Long term persistence of inflammation in children vaccinated with Salmonella conjugate vaccine is associated with augmented Th9-Th17 cytokine. Balaji C, Kevinkumar V, Aravindhan V. Cytokine 91 2017 128-131
14 Cell Type-Specific Immunomodulation Induced by Helminthes: Effect on Metainflammation, Insulin Resistance and Type-2 Diabetes. Aravindhan V, Anand G. Am J Trop Med Hyg. 97(6) 2017 1650-1661
15 Increased serum levels of novel T cell cytokines IL-33, IL-9 and IL-17 in subjects with type-1 diabetes. Shruthi S, Mohan V, Amutha A, Aravindhan V. Cytokine 86 2016 6-9
16 Metainflammation in Diabetic Coronary Artery Disease: Emerging Role of Innate and Adaptive Immune Responses. Aravindhan V, Madhumitha H. J Diabetes Res 2016 2016 6264149
17 Genetic association of IL-6, TNF-α and SDF-1 polymorphisms with serum cytokine levels in diabetic foot ulcer.  Dhamodharan U, Viswanathan V, Krishnamoorthy E, Rajaram R, Aravindhan V. Gene 565(1) 2015 62-7
18 Impaired toll-like receptor signalling in peripheral B cells from newly diagnosed type-2 diabetic subjects. Madhumitha H, Mohan V, Kumar NP, Pradeepa R, Babu S, Aravindhan V. Cytokine 76(2) 2015 253-259
19 Chronic Endotoxemia in Subjects with Type-1 Diabetes Is Seen Much before the Onset of Microvascular Complications. Aravindhan V, Mohan V, Arunkumar N, Sandhya S, Babu S. PLoS One 10(9) 2015 e0137618
20 A Study on Longevity of Immune Response after Vaccination with Salmonella Typhi Vi Conjugate Vaccine (Pedatyph™) in Children.  Chinnasami B, Sadasivam K, Vivekanandhan A, Arunachalam P, Pasupathy S. J Clin Diagn Res. 9(5) 2015 SC01-3
21 TLR-induced secretion of novel cytokine IL-27 is defective in newly diagnosed type-2 diabetic subjects. Madhumitha H, Mohan V, Babu S, Aravindhan V. Cytokine 1017

Books (Total Books: 2)

# Title Author Publisher Volume Year Page(s)
1 Chemokines at the Crossroad of Diabetes-Tuberculosis Synergy Vivekanandhan Aravindhan, Srinivasan Yuvaraj IntechOpen IntechOpen 2022
2 Helminth Induced Immunomodulation against Metainflammation and Insulin Resistance Vivekanandhan Aravindhan and Sibi Joy Manohar. IntechOpen IntechOpen 2021

Journals (Total Journals: 19)

# Title Author Publisher Volume Year Page(s)
1 Serum IL-9, IL-17, and TGF-β levels in subjects with diabetic kidney disease (CURES-134). PMID:25542095 Vasanthakumar R, Mohan V, Anand G, Deepa M., Babu S and Aravindhan V.* Cytokine 72(1) 2015, Mar 109-12
2 Increased Th1 and suppressed Th2 serum cytokine levels in subjects with diabetic coronary artery disease. PMID:24383855 Madhumitha H, Mohan V, Deepa M, Babu S and Aravindhan V.* Cardiovascular Diabetology. 13 2014 Jan 3 1-8
3 Increased IL-12 and decreased IL-33 serum levels are associated with increased Th1 and suppressed Th2 cytokine profile in patients with diabetic nephropathy (CURES-134). PMID:25550844 Anand G, Vasanthakumar R., Mohan V., Babu S. and Aravindhan V.* Int J Clin Exp Pathol 7(11) 2014 8008-8015
4 Serum adiponectin helps to differentiate type 1 and type 2 diabetes among young asian indians. PMID:23902401 Gokulakrishnan K, Aravindhan V, Amutha A, Abhijit S, Ranjani H, Anjana RM, Unnikrishnan R, Miranda P, Narayan KM, Mohan V. Diabetes Technol Ther. 15 (8) 2013 Aug 696-702
5 Effect of filarial infection on serum inflammatory and atherogenic biomarkers in coronary artery disease (CURES-121). PMID:22556082 Aravindhan V*, Mohan V, Surendar J, Rao MM, Anuradha R, Deepa M, Babu S. Am J Trop Med Hyg. 86(5) 2012 May 828-33
6 Increased levels of serum granulocyte-macrophage colony-stimulating factor is associated with activated peripheral dendritic cells in type 2 diabetes subjects (CURES-99).  PMID:22149626 Surendar J, Mohan V, Pavankumar N, Babu S, Aravindhan V.* Diabetes Technol Ther. 14(4) 2012 Apr 344-9
7 Circulating levels of high molecular weight (HMW) adiponectin and total adiponectin in relation to fat distribution, oxidative stress and inflammation in Asian Indians. PMID:22960344 Indulekha K, Surendar J, Anjana RM, Gokulakrishnan K, Balasubramanyam M, Aravindhan V, Mohan V. Dis Markers. 33(4) 2012 185-92
8 Increased levels of both Th1 and Th2 cytokines in subjects with metabolic syndrome (CURES-103). PMID:21355722 Surendar J, Mohan V, Rao MM, Babu S, Aravindhan V.* Diabetes Technol Ther. 13(4) 2011 Apr 477-82
9 Decreased serum interleukin-17 and increased transforming growth factor-β levels in subjects with metabolic syndrome (Chennai Urban Rural Epidemiology Study-95). PMID:20667562 Surendar J, Aravindhan V*, Rao MM, Ganesan A, Mohan V. Metabolism. 60(4) 2011 Apr 586-90
10 Association of cystatin-C with metabolic syndrome in normal glucose-tolerant subjects (CURES-97). PMID:20879967 Surendar J, Indulekha K, Aravindhan V, Ganesan A, Mohan V. Diabetes Technol Ther. 12(11) 2010 Nov 907-12
11 Decreased prevalence of lymphatic filariasis among diabetic subjects associated with a diminished pro-inflammatory cytokine response (CURES 83). PMID:20559443 Aravindhan V*, Mohan V, Surendar J, Muralidhara Rao M, Pavankumar N, Deepa M, Rajagopalan R, Kumaraswami V, Nutman TB, Babu S. PLoS Negl Trop Dis. 4(6) 2010 Jun 15 e707
12 Decreased prevalence of lymphatic filariasis among subjects with type-1 diabetes. PMID:21118945 Aravindhan V*, Mohan V, Surendar J, Rao MM, Ranjani H, Kumaraswami V, Nutman TB, Babu S. Am J Trop Med Hyg. 83(6) 2010 Dec 1336-9
13 Cystatin C and cystatin glomerular filtration rate as markers of early renal disease in Asian Indian subjects with glucose intolerance (CURES-32). PMID:19419268 Surendar J, Anuradha S, Ashley B, Balasubramanyam M, Aravindhan V, Rema M, Mohan V. Metab Syndr Relat Disord. 7(5) 2009 Oct 419-25
14 Mycobacterium tuberculosis groE promoter controls the expression of the bicistronic groESL1 operon and shows differential regulation under stress conditions. PMID:19222581 Aravindhan V, Christy AJ, Roy S, Ajitkumar P, Narayanan PR, Narayanan S. FEMS Microbiol Lett. 292(1) 2009 Mar 42-9
15 Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: Implications for vaccines. PMID:18845682 Zhu Q, Egelston C, Vivekanandhan A, Uematsu S, Akira S, Klinman DM, Belyakov IM, Berzofsky JA. Proc Natl Acad Sci U S A. 105(42) 2008 Oct 9. 16260–16265
16 Identification & differentiation of Mycobacterium avium & M. intracellulare by PCR- RFLP assay using the groES gene. PMID:18219086 Aravindhan V, Sulochana S, Narayanan S, Paramasivam CN, Narayanan PR. Indian J Med Res. 126(6) 2007 Dec 575-9
17 T-h-2 immunity and CD3+CD45RBlow-activated T cells in mice immunized with recombinant bacillus Calmette-Guérin expressing HIV-1 principal neutralizing determinant epitope. PMID:16706787 Aravindhan V, Narayanan S, Gautham N, Prasad V, Kannan P, Jacobs WR Jr, Narayanan P. FEMS Immunol Med Microbiol. 47(1) 2006 Jun 45-55
18 In-vivo study on “Dual Signal Hypothesis” & its correlation to humoral immune response using mycobacterial antigen. Aravindhan V. and Sulochana Das. Current Science 81(3) 2001 Aug 301-304
19   Increased Levels of Endotoxin Core Antibodies and Decreased Levels of sCD 14 Indicate Chronic Endotoxemia in Coronary Artery Disease (CURES-127). Aravindhan V.*, Mohan V, Madhumitha H, Valarmathi S, Babu S J Clin Exp Cardiolog 4 2013 July 264
// FLASH NEWS //
  • University of Madras attains category - 1 status from UGC |  NIRF Ranking - Ranked 39 in University Category 2024 |  University of Madras has been graded A++ in the NAAC Assessment

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