1 |
Diet-Derived Advanced Glycation End Products (DAGEs) Induce Proinflammatory Cytokine Expression in Cardiac and Renal Tissues of Experimental Mice: Protective Effect of Curcumin |
Sowndhar Rajan, Boopathi, Kalaiselvi Krishnan, Elangovan Vellaichamy |
Cardiovascular Toxicology |
22,1 |
2022 |
35-51 |
2 |
Divergent Synthesis and Evaluation of the in?vitro Cytotoxicity Profiles of 3,4-Ethylenedioxythiophenyl-2-propen-1-one Analogues. |
Karunakaran J, Dhatchana Moorthy N, Chowdhury SR, Iqbal S, Majumder HK, Gunasekaran K, Vellaichamy E, Mohanakrishnan AK. |
Journal |
ChemMedChem |
2019 |
1418-1430 |
3 |
Insights into the apatite mineralization potential of thermally processed nanocrystalline Ca10_xFex(PO4)6(OH)2. |
G. Radha, Balaji Venkatesan, Elangovan Vellaichamy and S.Balakumar |
Journal |
New J. Chem |
2019 |
1358--1371 |
4 |
Diet with high content of advanced glycation end products induces systemic inflammation and weight gain in experimental mice: Protective role of curcumin and gallic acid. |
Sowndhar Rajan B, Manivasagam S, Dhanusu S, Chandrasekar N, Krishna K, Kalaiarasu LP, Babu AA, Vellaichamy E. |
Journal |
Food Chem Toxicol |
2018 |
114:237-245 |
5 |
Synthesis and Biological Evaluation of Calothrixins B and their Deoxygenated Analogues. |
Muthu Ramalingam B, Dhatchana Moorthy N, Chowdhury SR, Mageshwaran T, Vellaichamy E, Saha S, Ganesan K, Rajesh BN, Iqbal S, Majumder HK, Gunasekaran K, Siva R, Mohanakrishnan AK. |
Journal |
J Med Chem |
2018 |
1285-1315 |
6 |
Novel isothiacalothrixin B analogues exhibit cytotoxic activity on human colon cancer cells in vitro by inducing irreversible DNA damage. |
Dhatchana Moorthy N, Muthu Ramalingam B, Iqbal S, Mohanakrishnan AK, Gunasekaran K, Vellaichamy E. |
Journal |
PLoS One |
2018 |
e0202903 |
7 |
Suppression of Npr1, not Npr2 gene function induces hypertrophic growth in H9c2 cells in vitro. |
Manivasagam S, Vellaichamy E. |
Journal |
Biochem Biophys Res Commu |
2017 |
250-256 |
8 |
Valporic acid enhances the Atrial Natriuretic Peptide (ANP) mediated anti-hypertrophic activity by modulating the Npr1 gene transcription in H9c2 cells in vitro. |
Manivasagam S, Velusamy T, Sowndharajan B, Chandrasekar N, Dhanusu S, Vellaichamy E. |
Journal |
Eur J Pharmacol. |
2017 |
94-104 |
9 |
Transient silencing of Npr3 gene expression improved the circulatory levels of atrial natriuretic peptides and attenuated β-adrenoceptor activation- induced cardiac hypertrophic growth in experimental rats. |
enkatesan B, Tumala A, Subramanian V, Vellaichamy E. |
Journal |
Eur J Pharmacol |
2017 |
44-58 |
10 |
Data on synthesis and characterization of chitosan nanoparticles for in vivo delivery of siRNA-Npr3: Targeting NPR-C expression in the heart. |
Venkatesan B, Tumala A, Subramanian V, Vellaichamy E. |
Journal |
Data Brief. |
2016 |
441-7 |
11 |
Differential expression and regulation of anti-hypertrophic genes Npr1 and Npr2 during β-adrenergic receptor activation-induced hypertrophic growth in rats. |
Manivasagam S, Subramanian V, Tumala A, Vellaichamy E. |
Journal |
Mol Cell Endocrinol |
2016 |
117-29 |
12 |
Insight into the Anti-Inflammatory Mechanism of Action of Atrial Natriuretic Peptide, a Heart Derived Peptide Hormone: Involvement of COX-2, MMPs, and NF-kB Pathways. |
Lakshmi Priya Kalaiarasu, Vimala Subramanian, Boopathi Sowndharrajan, Elangovan Vellaichamy. |
Journal |
Int J Pept Res Ther |
2016 |
016-9525-9 |
13 |
Synthesis of Thia-Analogues of Calothrixin B Involving FeCl3-Mediated Domino Reaction. |
Bose Muthu Ramalingam, Nachiappan Dhatchana Moorthy, Elangovan Vellaichamy, Arasambattu K. Mohanakrishnan. |
Journal |
synlett |
2016 |
|
14 |
Atrial natriuretic peptide (ANP) inhibits DMBA/croton oil induced skin tumor growth by modulating NF-kB, MMPs, and infiltrating mast cells in Swiss albino mice. |
Subramanian, V and Vellaichamy E |
European Journal of Pharmacology |
740 |
2014 |
388-397 |
15 |
Aminoguanidine inhibits ventricular fibrosis and remodeling process in isoproterenol- induced hypetrophied rats hearts by supressing ROS and MMPs. |
Parthasarathy A, Gopi V, Shyamala Devi KM, and Vellaichamy E |
Life Sciences |
118 |
2014 |
217-228 |
16 |
Topical application of 7, 12, DMBA/croton oil induced two step carcinogenesis by modulating antioxidants and MMP-2/MMP-9 in swiss albino mice. |
1.Subramanian V, Venkatesan B,Tumala A, Vellaichamy E. |
Food and chemical toxicology, |
66 |
2014 |
44-55 |
17 |
Synthesis and cardio protective biological applications of glucodendrimers by H9C2 cell studies |
3. Rajakumar P, Anandhan R, Vadla GP, Vellaichamy E. |
Carbohydr Polym. |
99 |
2014 |
403-14 |
18 |
Supression of natriuretic peptide receptor-A upregualtes Ang II induced collagen synthesis in adult cardiac fibroblasts. |
1. Parthasarathy A, Gopi V Umadevi S, Vellaichamy E |
Molecular cellular Biochemsitry, March 2013 |
(accepted for publication) |
2013 |
|
19 |
Ang II down regulates natriuretic peptide receptor-A mediated antihypertrophic signaling in experimental rat hearts. |
Parthasarathy A, Gopi V Umadevi S, Vellaichamy E |
Indian J of experimental biology, |
51 |
2013 |
48-55 |
20 |
Studies on the cardio protective role of gallic acid ahainst AGE-induced cell proliferation and oxidative stress in H9C2 cells. |
Umadevi S, Atika S, Gopi V, Elangovan V |
Cardiovasc Toxicol. |
12: |
2012 |
304-311 |
21 |
Induction of renal damage and modulation of redox potential in rats infused with glyoxal. |
Umadevi S, Atika S, Gopi V, Elangovan V |
Biomedicine and preventive nutrition |
2 |
2012 |
119-124 |
22 |
Antifibrotic cardioprotective efficacy of aminoguanidine against streptozotozin-indced cardiac fibrosis and high glucose induced collagen up regulation in cardiac fibroblasts. |
Vadia GP, Vellaichamy E. |
Chem Biol Interact |
197 |
2012 |
119-28 |
23 |
Regulation of cardiac ACE and AT receptor gene expression in Npr1 gene-disrupted mice. |
1. Pandey KN, Vellaichamy E |
Clin Exp Pharmacol Physiol. |
37: |
2010 |
e70-7 |
24 |
Guanylyl cyclase/natriuretic peptide receptor-A gene disruption causes increased adrenal angiotensin II and aldosterone levels |
Zhao D, Vellaichamy E, Somanna NK, Pandey KN |
Am J Physiol Renal Physiol. |
293 |
2007 |
F121-7 |
25 |
Disruption of guanylyl cyclase /natriuretic peptide receptor-A gene up regulate AT1 receptor signaling in null mutatant mice: Role in cardiac hypertrophy. |
2. Vellaichamy E, Zhao D, Somanna N, and Pandey KN |
Physiol Genomics. |
31(2) |
2007 |
193-202 |
26 |
Enhanced activation of pro-inflammatory cytokines in mice lacking natriuretic peptide receptor-A |
4. Vellaichamy E, Kaur K, Pandey KN. |
Peptides. |
28(4) |
2007 |
893-889 |
27 |
Involvement of NF-kB/matrix metalloproteinase pathway in fibrosis of mice lacking and pro-guanylyl cyclase/natriuretic peptide receptor-A |
Vellaichamy E, Khurana ML, Fink J and Pandey KN |
J. Biol. Chem., |
280 |
2005 |
19230-42. |
28 |
Reduced cGMP signaling activates of nuclear factor kappa-B in hypertrophied hearts of mice lacking natriuretic peptide receptor-A, |
Vellaichamy E, Somanna NK, Pandey, KN. |
Biochem Biophys Res Commun, |
327: |
2005 |
106-111. |
29 |
Influence of cytokines and growth factors in ANG II-mediated collagen up regulation by fibroblasts in rats: role of myocytes. |
Sarkar S, Vellaichamy E, Young D, Sen S. |
Am J Physiol Heart Circ Physiol. |
287 |
2004, |
H107-17 |
30 |
Natriuretic peptide receptor A mediates renal sodium excretory responses to blood volume expansion. |
Shi SJ, Vellaichamy E, Chin SY, Smithies O, Navar LG, Pandey KN |
Am J Physiol Renal Physiol. |
285 |
2003 |
F694-702 |
31 |
Role of myocytes in myocardial collagen production. |
Pathak M, Sarkar S, Vellaichamy E, Sen S. |
Hypertension |
37 |
2001 |
833-40 |
32 |
Quantification of the overall reactive oxygen species scavenging capacity of biological fluids and tissues. |
Kohen R, Vellaichamy E, Hrbac J, Gati I, Tirosh O. |
Free Radic Biol Med. |
28 |
2000 |
871-879 |
33 |
Neurological recovery from closed head injury is impaired in diabetic rats. |
Elangovan V, Kohen R, Shohami E. |
J Neurotrauma, |
17 |
2000 |
1013-1027 |
34 |
Increased hepatic lipid soluble antioxidant capacity as compared to other organs of streptozotocin- induced diabetic rats: a cyclic voltammetry study. |
Elangovan V, Shohami E, Gati I, Kohen R. |
Free Radic Res. |
32 |
2000 |
125-134 |
35 |
Antineoplastic effect of quercetin on sarcoma-180 solid tumor. |
Ravichandran P, Elangovan V, and Govindasamy S. |
Journal Clinical Biochemistry and Nutrition, |
22 |
1997 |
130-135 |
36 |
Fluorescence spectroscopic identification of 7, 12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis. |
Balasubramanian S, Elangovan V, and Govindasamy S. |
Carcicogenesis |
16 |
1995 |
2461-2465 |
37 |
In vitro studies on the anticancer activity of Baccopa manniera extracts using S-180 cell lines. |
Elangovan V, Govindasamy S |
Fitoterapia |
66 |
1995 |
211-215 |
38 |
Chemo preventive potential of dietary bioflavonoids against 20-methylcholanthrene-induced tumorigenesis. |
Elangovan V, Sekar N, Govindasamy S |
Cancer Lett. |
87 |
1994 |
107-113 |
39 |
Antiproliferative effect of some bioflavonoidal compounds against HEp-2 and S-180 cell lines, |
Elangovan V, Sekar N, Govindasamy S. |
Indian Journal of Pharmacology, |
26 |
1994 |
261-269 |
40 |
Chemopreventive potential of some naturally occurring bioflavonoids on 7, 12-dimethylbenz[a]anthracene-induced carcinogenesis in mouse skin, |
Elangovan V, Balasubramanian S, Sekar N, Govindasamy S. |
Journal of Clinical Biochemistry and Nutrition, |
17 |
1994 |
153-160 |
41 |
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