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From the Desk of the Vice Chancellor

Greetings!

As the Vice Chancellor of this premier university, I am extremely pleased to share this space to converse with all of you. The University of Madras is a post- sesquicentennial institution which has forged a glorious path for itself and has been the site for significant scientific discoveries as well as the beacon for national and regional societal transformation. It has successfully managed to hold aloft its tradition even while keeping up with the emerging trends. One reason for this is the way in which the university has kept alive its interactions with all the stakeholders.

The COVID 19 pandemic has introduced a ‘new normal’ and its impact is felt in the workings of the university as well. The students have been attending the lectures online. While online learning has the advantage of being anytime and anywhere, it has taken away the peer group interaction and peer learning which are integral aspects of the university experience. We look forward to welcoming you to the campus very soon. Meanwhile, our faculty and administration will continue to bring the best to the virtual classrooms. As students, you need to view the restrictions posed by the pandemic as a temporary deterrent. Your focus should be to gain the competencies to conduct application oriented research in order to evolve as useful citizens of our society.

Our university boasts of faculty with a high degree of knowledge and commitment to offer the best in teaching and research. Given the context of the pandemic, we need to redefine our teaching-learning processes to offer the best pedagogic experience to our students. Similarly, the post-pandemic era demands that we hone the employment potential and entrepreneurial capacity of our learners. This necessitates that we focus on sponsored research in cutting edge areas.

Our administrative staff have been the backbone of the university. While we move towards a transparent and complete e-governance model, we need more support from you. When the teaching-learning process at our university – from admission to certification -- is moving into the digital era, your skills and competencies need to keep pace.

At our university, we are gearing up for the final round of NAAC re-accreditation. This has offered us an opportunity to assess our Strengths, Weaknesses, Opportunities and Challenges. Further, it has made us more determined to reiterate our quality benchmarks in teaching, research and extension activities. We are aware of this responsibility and fully prepared for it because, our university has always encouraged individual thinking within the established frameworks. This is echoed in the words of Tim Burners Lee, who initiated the World Wide Web: “We are forming cells within a global brain and we are excited that we might start to think collectively. What becomes of us still hangs crucially on how we think individually.” Let us unite to make the educational experience at the University of Madras a synergy of the best minds and best thoughts.

Prof.Dr.S.Gowri

Vice-Chancellor
University of Madras

Dr. Elangovan VellaichamyM.Sc., M.Phil., Ph.D

Professor
Department of Biochemistry
7

Awards

42

Publications

16

Seminars / Conference

8

Projects

6

Ph.D Awarded

0

Ph.D Present

Publications

Books (Total Books: 1)

# Title Author Publisher Volume Year Page(s)
1 Quantification of overall oxygen scavenging capacity of biological fluid and tissues Kohen R, Vellaichamy E, Hrbac J, Gati I, Tirosh O. Bioassay for oxidative stress status (BOSS) Elsevier Sciecnes B.V 2001 131-139

Journals (Total Journals: 41)

# Title Author Publisher Volume Year Page(s)
1 Diet-Derived Advanced Glycation End Products (DAGEs) Induce Proinflammatory Cytokine Expression in Cardiac and Renal Tissues of Experimental Mice: Protective Effect of Curcumin Sowndhar Rajan, Boopathi, Kalaiselvi Krishnan, Elangovan Vellaichamy Cardiovascular Toxicology 22,1 2022 35-51
2  Divergent Synthesis and Evaluation of the in?vitro Cytotoxicity Profiles of 3,4-Ethylenedioxythiophenyl-2-propen-1-one Analogues.  Karunakaran J, Dhatchana Moorthy N, Chowdhury SR, Iqbal S, Majumder HK, Gunasekaran K, Vellaichamy E, Mohanakrishnan AK. Journal ChemMedChem 2019 1418-1430
3 Insights into the apatite mineralization potential of thermally processed nanocrystalline Ca10_xFex(PO4)6(OH)2.  G. Radha, Balaji Venkatesan, Elangovan Vellaichamy and S.Balakumar Journal New J. Chem 2019 1358--1371
4 Diet with high content of advanced glycation end products induces systemic inflammation and weight gain in experimental mice: Protective role of curcumin and gallic acid.  Sowndhar Rajan B, Manivasagam S, Dhanusu S, Chandrasekar N, Krishna K, Kalaiarasu LP, Babu AA, Vellaichamy E. Journal Food Chem Toxicol 2018 114:237-245
5 Synthesis and Biological Evaluation of Calothrixins B and their Deoxygenated Analogues.  Muthu Ramalingam B, Dhatchana Moorthy N, Chowdhury SR, Mageshwaran T, Vellaichamy E, Saha S, Ganesan K, Rajesh BN, Iqbal S, Majumder HK, Gunasekaran K, Siva R, Mohanakrishnan AK. Journal J Med Chem 2018 1285-1315
6 Novel isothiacalothrixin B analogues exhibit cytotoxic activity on human colon cancer cells in vitro by inducing irreversible DNA damage.  Dhatchana Moorthy N, Muthu Ramalingam B, Iqbal S, Mohanakrishnan AK, Gunasekaran K, Vellaichamy E. Journal PLoS One 2018 e0202903
7 Suppression of Npr1, not Npr2 gene function induces hypertrophic growth in H9c2 cells in vitro.  Manivasagam S, Vellaichamy E. Journal Biochem Biophys Res Commu 2017 250-256
8 Valporic acid enhances the Atrial Natriuretic Peptide (ANP) mediated anti-hypertrophic activity by modulating the Npr1 gene transcription in H9c2 cells in vitro.  Manivasagam S, Velusamy T, Sowndharajan B, Chandrasekar N, Dhanusu S, Vellaichamy E. Journal Eur J Pharmacol. 2017 94-104
9 Transient silencing of Npr3 gene expression improved the circulatory levels of atrial natriuretic peptides and attenuated β-adrenoceptor activation- induced cardiac hypertrophic growth in experimental rats.  enkatesan B, Tumala A, Subramanian V, Vellaichamy E. Journal Eur J Pharmacol 2017 44-58
10 Data on synthesis and characterization of chitosan nanoparticles for in vivo delivery of siRNA-Npr3: Targeting NPR-C expression in the heart.  Venkatesan B, Tumala A, Subramanian V, Vellaichamy E. Journal Data Brief. 2016 441-7
11 Differential expression and regulation of anti-hypertrophic genes Npr1 and Npr2 during β-adrenergic receptor activation-induced hypertrophic growth in rats.  Manivasagam S, Subramanian V, Tumala A, Vellaichamy E. Journal Mol Cell Endocrinol 2016 117-29
12 Insight into the Anti-Inflammatory Mechanism of Action of Atrial Natriuretic Peptide, a Heart Derived Peptide Hormone: Involvement of COX-2, MMPs, and NF-kB Pathways. Lakshmi Priya Kalaiarasu, Vimala Subramanian, Boopathi Sowndharrajan, Elangovan Vellaichamy. Journal Int J Pept Res Ther 2016 016-9525-9
13 Synthesis of Thia-Analogues of Calothrixin B Involving FeCl3-Mediated Domino Reaction. Bose Muthu Ramalingam, Nachiappan Dhatchana Moorthy, Elangovan Vellaichamy, Arasambattu K. Mohanakrishnan. Journal synlett 2016
14 Atrial natriuretic peptide (ANP) inhibits DMBA/croton oil induced skin tumor growth by modulating NF-kB, MMPs, and infiltrating mast cells in Swiss albino mice. Subramanian, V and Vellaichamy E European Journal of Pharmacology 740 2014 388-397
15 Aminoguanidine inhibits ventricular fibrosis and remodeling process in isoproterenol- induced hypetrophied rats hearts by supressing ROS and MMPs. Parthasarathy A, Gopi V, Shyamala Devi KM, and Vellaichamy E Life Sciences 118 2014 217-228
16 Topical application of  7, 12, DMBA/croton oil induced two step carcinogenesis by modulating antioxidants and MMP-2/MMP-9 in swiss albino mice. 1.Subramanian V, Venkatesan B,Tumala A, Vellaichamy E. Food and chemical toxicology, 66 2014 44-55
17 Synthesis and cardio protective biological applications of glucodendrimers by H9C2 cell studies 3. Rajakumar P, Anandhan R, Vadla GP, Vellaichamy E. Carbohydr Polym. 99 2014 403-14
18 Supression of natriuretic peptide receptor-A upregualtes Ang II induced collagen synthesis in adult cardiac fibroblasts. 1. Parthasarathy A, Gopi V Umadevi S, Vellaichamy E Molecular cellular Biochemsitry, March 2013 (accepted for publication) 2013
19 Ang II  down regulates natriuretic peptide receptor-A mediated antihypertrophic signaling in experimental rat hearts. Parthasarathy A, Gopi V Umadevi S, Vellaichamy E Indian J of experimental biology, 51 2013 48-55
20 Studies on the cardio protective role of gallic acid ahainst AGE-induced cell proliferation and oxidative stress in H9C2 cells. Umadevi S, Atika S, Gopi V, Elangovan V Cardiovasc Toxicol. 12: 2012 304-311
21 Induction of renal damage and modulation of redox potential in rats infused with glyoxal. Umadevi S, Atika S, Gopi V, Elangovan V Biomedicine and preventive nutrition 2 2012 119-124
22 Antifibrotic cardioprotective efficacy of aminoguanidine against streptozotozin-indced cardiac fibrosis and high glucose induced collagen up regulation in cardiac fibroblasts. Vadia GP, Vellaichamy E. Chem Biol Interact 197 2012 119-28
23   Regulation of cardiac ACE and AT receptor gene expression in Npr1 gene-disrupted mice. 1. Pandey KN, Vellaichamy E Clin Exp Pharmacol Physiol. 37: 2010 e70-7
24 Guanylyl cyclase/natriuretic peptide receptor-A gene disruption causes increased  adrenal angiotensin II and aldosterone levels Zhao D, Vellaichamy E, Somanna NK, Pandey KN Am J Physiol Renal Physiol. 293 2007 F121-7
25      Disruption of guanylyl cyclase /natriuretic peptide receptor-A gene up regulate AT1 receptor signaling in null mutatant mice: Role in cardiac hypertrophy. 2. Vellaichamy E, Zhao D, Somanna N, and Pandey KN Physiol Genomics. 31(2) 2007 193-202
26 Enhanced activation of pro-inflammatory cytokines in mice lacking natriuretic peptide receptor-A 4. Vellaichamy E, Kaur K, Pandey KN. Peptides. 28(4) 2007 893-889
27 Involvement of NF-kB/matrix metalloproteinase pathway in fibrosis of mice lacking  and pro-guanylyl cyclase/natriuretic peptide receptor-A Vellaichamy E, Khurana ML, Fink J and Pandey KN J. Biol. Chem., 280 2005 19230-42.
28 Reduced cGMP signaling activates of  nuclear factor kappa-B in hypertrophied hearts of mice lacking natriuretic peptide receptor-A, Vellaichamy E, Somanna NK, Pandey, KN. Biochem Biophys Res Commun, 327: 2005 106-111.
29 Influence of cytokines and growth factors in ANG II-mediated collagen up regulation by fibroblasts in rats: role of myocytes. Sarkar S, Vellaichamy E, Young D, Sen S. Am J Physiol Heart Circ Physiol. 287 2004, H107-17
30 Natriuretic peptide receptor A mediates renal sodium excretory responses to blood volume expansion. Shi SJ, Vellaichamy E, Chin SY, Smithies O, Navar LG, Pandey KN Am J Physiol Renal Physiol. 285 2003 F694-702
31 Role of myocytes in myocardial collagen production. Pathak M, Sarkar S, Vellaichamy E, Sen S. Hypertension 37 2001 833-40
32 Quantification of the overall reactive oxygen species scavenging capacity of biological fluids and tissues. Kohen R, Vellaichamy E, Hrbac J, Gati I, Tirosh O. Free Radic Biol Med. 28 2000 871-879
33 Neurological recovery from closed head injury is impaired in diabetic rats. Elangovan V, Kohen R, Shohami E. J Neurotrauma, 17 2000 1013-1027
34 Increased hepatic lipid soluble antioxidant capacity as compared to other organs of streptozotocin- induced diabetic rats: a cyclic voltammetry study. Elangovan V, Shohami E, Gati I, Kohen R. Free Radic Res. 32 2000 125-134
35 Antineoplastic effect of quercetin on sarcoma-180 solid tumor. Ravichandran P, Elangovan V, and Govindasamy S. Journal Clinical Biochemistry and Nutrition, 22 1997 130-135
36 Fluorescence spectroscopic identification of 7, 12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis. Balasubramanian S, Elangovan V, and Govindasamy S. Carcicogenesis 16 1995 2461-2465
37 In vitro studies on the anticancer activity of Baccopa manniera extracts using S-180 cell lines. Elangovan V, Govindasamy S Fitoterapia 66 1995 211-215
38 Chemo preventive potential of dietary bioflavonoids against 20-methylcholanthrene-induced tumorigenesis. Elangovan V, Sekar N, Govindasamy S Cancer Lett. 87 1994 107-113
39 Antiproliferative effect of some bioflavonoidal compounds against HEp-2 and S-180 cell lines, Elangovan V, Sekar N, Govindasamy S. Indian Journal of Pharmacology, 26 1994 261-269
40 Chemopreventive potential of some naturally occurring  bioflavonoids on 7, 12-dimethylbenz[a]anthracene-induced carcinogenesis in mouse skin, Elangovan V, Balasubramanian S, Sekar N, Govindasamy S. Journal of Clinical Biochemistry and Nutrition, 17 1994 153-160
41
// FLASH NEWS //
  • University of Madras attains category - 1 status from UGC |  NIRF Ranking - Ranked 39 in University Category 2024 |  University of Madras has been graded A++ in the NAAC Assessment

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