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From the Desk of the Vice Chancellor

Greetings!

As the Vice Chancellor of this premier university, I am extremely pleased to share this space to converse with all of you. The University of Madras is a post- sesquicentennial institution which has forged a glorious path for itself and has been the site for significant scientific discoveries as well as the beacon for national and regional societal transformation. It has successfully managed to hold aloft its tradition even while keeping up with the emerging trends. One reason for this is the way in which the university has kept alive its interactions with all the stakeholders.

The COVID 19 pandemic has introduced a ‘new normal’ and its impact is felt in the workings of the university as well. The students have been attending the lectures online. While online learning has the advantage of being anytime and anywhere, it has taken away the peer group interaction and peer learning which are integral aspects of the university experience. We look forward to welcoming you to the campus very soon. Meanwhile, our faculty and administration will continue to bring the best to the virtual classrooms. As students, you need to view the restrictions posed by the pandemic as a temporary deterrent. Your focus should be to gain the competencies to conduct application oriented research in order to evolve as useful citizens of our society.

Our university boasts of faculty with a high degree of knowledge and commitment to offer the best in teaching and research. Given the context of the pandemic, we need to redefine our teaching-learning processes to offer the best pedagogic experience to our students. Similarly, the post-pandemic era demands that we hone the employment potential and entrepreneurial capacity of our learners. This necessitates that we focus on sponsored research in cutting edge areas.

Our administrative staff have been the backbone of the university. While we move towards a transparent and complete e-governance model, we need more support from you. When the teaching-learning process at our university – from admission to certification -- is moving into the digital era, your skills and competencies need to keep pace.

At our university, we are gearing up for the final round of NAAC re-accreditation. This has offered us an opportunity to assess our Strengths, Weaknesses, Opportunities and Challenges. Further, it has made us more determined to reiterate our quality benchmarks in teaching, research and extension activities. We are aware of this responsibility and fully prepared for it because, our university has always encouraged individual thinking within the established frameworks. This is echoed in the words of Tim Burners Lee, who initiated the World Wide Web: “We are forming cells within a global brain and we are excited that we might start to think collectively. What becomes of us still hangs crucially on how we think individually.” Let us unite to make the educational experience at the University of Madras a synergy of the best minds and best thoughts.

Prof.Dr.S.Gowri

Vice-Chancellor
University of Madras

Department of Genetics

Dr.V.AravindhanM.Sc., M.Phil., Ph.D.

Assistant professor

Dr.V.Aravindhan is Assistant professor in the Department of Genetics, University of Madras. He/She has graduated in B.Sc (Zoology), M.Sc (Biomedical Genetics), NET-CSIR-JRF (Biology), M.Phil (Biochemistry), PhD (Genetic engineering and Immunology (interdisciplinary)), PDF (Molecular Immunology). Published 42 publications in Indian / international journals and papers in national/international seminars, organized & participated in 8 workshops/seminars. His/Her area of specialization is/are Diabetes, Tuberculosis, and Filariasis.Immunology, Immunogenetics, 

Address:

Dept of Genetics, Dr ALM PG IBMS, University of Madras Taramani, Chennai-600113. Fax: +91-44-2454070

Contact:

Phone: 044-24547060
Mobile: Not Available
Email: cvaravindan@unom.ac.in
cvaravindhan@gmail.com

Specialization

DIABETES

TUBERCULOSIS

FILARIASIS

IMMUNOLOGY

IMMUNOGENETICS

Qualification
  1. 2008

    PDF

    Molecular Immunology
  2. 2005

    PhD

    Genetic engineering and Immunology (interdisciplinary)
  3. 2000

    M.Phil

    Biochemistry
  4. 2000

    NET-CSIR-JRF

    Biology
  5. 1999

    M.Sc

    Biomedical Genetics
  6. 1996

    B.Sc

    Zoology
Experience
  1. 25/06/2010- 14/02/2014
    Scientist
    Anna University- KB Chandrashekar Research Foundation
  2. 16/04/2008- 14/06/2010
    Scientist
    Madras Diabetes Research Foundation
Acheivements
No data Found
Membership

National

  • RESEARCH SOCIETY FOR THE STUDY OF DIABETES IN INDIA www.rssdi.in
  • INDIAN IMMUNOLOGY SOCIETY http://www.indianimmunology.org/
  • The Indian Society of Human Genetics
Awards
  • Indo-German Fellowship, 
  • Best Reseacher Award in Diamond Jubille (60th Year) celebration, 
Research
  • Publications
  • Projects
  • Ph.D Scholars
  • Post Doctoral Scholar

Publications

Articles (Total Articles: 21)
  •   Serum levels of novel anti-inflammatory cytokine Interleukin-38 in diabetes patients infected with latent tuberculosis (DM-LTB-3).,  Aravindhan V*, Bobhate A, Sathishkumar K, Viswanathan V.,  J Diabetes Complications.,  36(3),  (2022),  108133
  • Emerging neuroprotective interventions in periventricular leukomalacia: A systematic review of preclinical studies.,  Abiramalatha T, Ramaswamy VV, Ponnala AK, Kallem VR, Murkunde YV, Punnoose AM, Vivekanandhan A, Pullattayil AK, Amboiram P.,  31(3),  Expert Opin Investig Drugs.,  (2022),  305-330
  •    RETRA induces necroptosis in cervical cancer cells through RIPK1, RIPK3, MLKL and increased ROS production.,  Mohanty S, Yadav P, Lakshminarayanan H, Sharma P, Vivekanandhan A, Karunagaran D.,  Epub ahead of print,  Eur J Pharmacol.,  (2022),  Epub ahead of print
  • Unique Reciprocal Association seen between Latent Tuberculosis Infection and Diabetes is due to Immunoendocrine Modulation (DM-LTB-1).,  1. Aravindhan V.*, Bobhate A., Sathishkumar K., Patil A., Kumpatla S. and Viswanathan V.,  Front. Microbiol.,  13:884374.,  (2022),  1-11
  • Decreased leukocyte exhaustion is associated with decreased IFN-β and increased α-defensin-1 levels in type-2 diabetes,  Shruthi S., Sibi J.M, Mohan V., Babu S., Nirmaladevi V., Aravindhan V*.,  Cytokine,  156:155918,  (2022),  1-12
  •  (2022) Modulatory effect of filarial infection on the systemic hormone levels in subjects with metabolic syndrome (DM-LF5).   doi: 10.3389/fendo.2022.1011942,  Sibi JM, Mohan V, Deepa M, Babu S and Aravindhan V,  Front. Endocrinol.,  13:1011942.,  (2022),  1-8
  •     Augmented Innate and Adaptive Immune Responses Under Conditions of Diabetes–Filariasis Comorbidity.,  Sibi JM, Mohan V, Munisankar S, Babu S and Aravindhan V*.,  Front. Immunol,  12:716515,  (2021),  1-12
  •          Anti-inflammatory cytokines IL-27, IL-10, IL-1Ra and TGF-β in subjects with increasing grades of glucose intolerence (DM-LTB-2)    ,  Bobhate A., Viswanathan V., Aravindhan V,  Cytokine,  (2021), 
  •   The Strange Case of BCG and COVID-19: The Verdict Is Still up in the Air.,  Gopalaswamy R., Ganesan N., Velmurugan K., Aravindhan V. and Subbian S.,  Vaccines.,  8 (4),  (2020),  612
  •        In silico identification and wet lab validation of novel cryptic B cell epitopes in ZnT8 zinc transporter autoantigen. Int J Biol Macromol. 2019 Apr 15;127:657-664.,  Shruthi S, Mohan V, RaoMaradana M, Aravindhan V,  Int J Biol Macromol,  127,  (2019),  657-664
  • Single nucleotide polymorphisms in cytokine/chemokine genes are associated with severe infection, ulcer grade and amputation in diabetic foot ulcer,  Viswanathan V*, Dhamodharan U, Srinivasan V, Rajaram R, Aravindhan V*.,  International Journal of Biological Macromolecules,  118,  (2018),  1995-2000
  • Serum levels of chemokines IP-10, IL-8 and SDF-1 serve as good biomarkers for diabetes-tuberculosis nexus  ,  Aravindhan V, Kevinkumar V, Dhamodharan U, Viswanathan V,  J Diabetes Complications,  Sep;32(9),  (2018),  857-862
  • Long term persistence of inflammation in children vaccinated with Salmonella conjugate vaccine is associated with augmented Th9-Th17 cytokine.,  Balaji C, Kevinkumar V, Aravindhan V.,  Cytokine,  91,  (2017),  128-131
  • Cell Type-Specific Immunomodulation Induced by Helminthes: Effect on Metainflammation, Insulin Resistance and Type-2 Diabetes.,  Aravindhan V, Anand G.,  Am J Trop Med Hyg.,  97(6),  (2017),  1650-1661
  • Increased serum levels of novel T cell cytokines IL-33, IL-9 and IL-17 in subjects with type-1 diabetes.,  Shruthi S, Mohan V, Amutha A, Aravindhan V.,  Cytokine,  86,  (2016),  6-9
  • Metainflammation in Diabetic Coronary Artery Disease: Emerging Role of Innate and Adaptive Immune Responses.,  Aravindhan V, Madhumitha H.,  J Diabetes Res,  2016,  (2016),  6264149
  • Genetic association of IL-6, TNF-α and SDF-1 polymorphisms with serum cytokine levels in diabetic foot ulcer. ,  Dhamodharan U, Viswanathan V, Krishnamoorthy E, Rajaram R, Aravindhan V.,  Gene,  565(1),  (2015),  62-7
  • Impaired toll-like receptor signalling in peripheral B cells from newly diagnosed type-2 diabetic subjects.,  Madhumitha H, Mohan V, Kumar NP, Pradeepa R, Babu S, Aravindhan V.,  Cytokine,  76(2),  (2015),  253-259
  • Chronic Endotoxemia in Subjects with Type-1 Diabetes Is Seen Much before the Onset of Microvascular Complications.,  Aravindhan V, Mohan V, Arunkumar N, Sandhya S, Babu S.,  PLoS One,  10(9),  (2015),  e0137618
  • A Study on Longevity of Immune Response after Vaccination with Salmonella Typhi Vi Conjugate Vaccine (Pedatyph™) in Children. ,  Chinnasami B, Sadasivam K, Vivekanandhan A, Arunachalam P, Pasupathy S.,  J Clin Diagn Res.,  9(5),  (2015),  SC01-3
  • TLR-induced secretion of novel cytokine IL-27 is defective in newly diagnosed type-2 diabetic subjects.,  Madhumitha H, Mohan V, Babu S, Aravindhan V.,  Cytokine,  (1017), 
Books (Total Books: 2)
  • Chemokines at the Crossroad of Diabetes-Tuberculosis Synergy,  Vivekanandhan Aravindhan, Srinivasan Yuvaraj,  IntechOpen,  IntechOpen,  (2022), )
  • Helminth Induced Immunomodulation against Metainflammation and Insulin Resistance,  Vivekanandhan Aravindhan and Sibi Joy Manohar.,  IntechOpen,  IntechOpen,  (2021), )

Journals (Total Journals: 19)

  • Serum IL-9, IL-17, and TGF-β levels in subjects with diabetic kidney disease (CURES-134). PMID:25542095,  Vasanthakumar R, Mohan V, Anand G, Deepa M., Babu S and Aravindhan V.*,  Cytokine,  72(1),  (2015, Mar),  109-12, 
  • Increased Th1 and suppressed Th2 serum cytokine levels in subjects with diabetic coronary artery disease. PMID:24383855,  Madhumitha H, Mohan V, Deepa M, Babu S and Aravindhan V.*,  Cardiovascular Diabetology.,  13,  (2014 Jan 3),  1-8, 
  • Increased IL-12 and decreased IL-33 serum levels are associated with increased Th1 and suppressed Th2 cytokine profile in patients with diabetic nephropathy (CURES-134). PMID:25550844,  Anand G, Vasanthakumar R., Mohan V., Babu S. and Aravindhan V.*,  Int J Clin Exp Pathol,  7(11),  (2014),  8008-8015, 
  • Serum adiponectin helps to differentiate type 1 and type 2 diabetes among young asian indians. PMID:23902401,  Gokulakrishnan K, Aravindhan V, Amutha A, Abhijit S, Ranjani H, Anjana RM, Unnikrishnan R, Miranda P, Narayan KM, Mohan V.,  Diabetes Technol Ther.,  15 (8),  (2013 Aug),  696-702, 
  • Effect of filarial infection on serum inflammatory and atherogenic biomarkers in coronary artery disease (CURES-121). PMID:22556082,  Aravindhan V*, Mohan V, Surendar J, Rao MM, Anuradha R, Deepa M, Babu S.,  Am J Trop Med Hyg.,  86(5),  (2012 May),  828-33, 
  • Increased levels of serum granulocyte-macrophage colony-stimulating factor is associated with activated peripheral dendritic cells in type 2 diabetes subjects (CURES-99).  PMID:22149626,  Surendar J, Mohan V, Pavankumar N, Babu S, Aravindhan V.*,  Diabetes Technol Ther.,  14(4),  (2012 Apr),  344-9, 
  • Circulating levels of high molecular weight (HMW) adiponectin and total adiponectin in relation to fat distribution, oxidative stress and inflammation in Asian Indians. PMID:22960344,  Indulekha K, Surendar J, Anjana RM, Gokulakrishnan K, Balasubramanyam M, Aravindhan V, Mohan V.,  Dis Markers.,  33(4),  (2012),  185-92, 
  • Increased levels of both Th1 and Th2 cytokines in subjects with metabolic syndrome (CURES-103). PMID:21355722,  Surendar J, Mohan V, Rao MM, Babu S, Aravindhan V.*,  Diabetes Technol Ther.,  13(4),  (2011 Apr),  477-82, 
  • Decreased serum interleukin-17 and increased transforming growth factor-β levels in subjects with metabolic syndrome (Chennai Urban Rural Epidemiology Study-95). PMID:20667562,  Surendar J, Aravindhan V*, Rao MM, Ganesan A, Mohan V.,  Metabolism.,  60(4),  (2011 Apr),  586-90, 
  • Association of cystatin-C with metabolic syndrome in normal glucose-tolerant subjects (CURES-97). PMID:20879967,  Surendar J, Indulekha K, Aravindhan V, Ganesan A, Mohan V.,  Diabetes Technol Ther.,  12(11),  (2010 Nov),  907-12, 
  • Decreased prevalence of lymphatic filariasis among diabetic subjects associated with a diminished pro-inflammatory cytokine response (CURES 83). PMID:20559443,  Aravindhan V*, Mohan V, Surendar J, Muralidhara Rao M, Pavankumar N, Deepa M, Rajagopalan R, Kumaraswami V, Nutman TB, Babu S.,  PLoS Negl Trop Dis.,  4(6),  (2010 Jun 15),  e707, 
  • Decreased prevalence of lymphatic filariasis among subjects with type-1 diabetes. PMID:21118945,  Aravindhan V*, Mohan V, Surendar J, Rao MM, Ranjani H, Kumaraswami V, Nutman TB, Babu S.,  Am J Trop Med Hyg.,  83(6),  (2010 Dec),  1336-9, 
  • Cystatin C and cystatin glomerular filtration rate as markers of early renal disease in Asian Indian subjects with glucose intolerance (CURES-32). PMID:19419268,  Surendar J, Anuradha S, Ashley B, Balasubramanyam M, Aravindhan V, Rema M, Mohan V.,  Metab Syndr Relat Disord.,  7(5),  (2009 Oct),  419-25, 
  • Mycobacterium tuberculosis groE promoter controls the expression of the bicistronic groESL1 operon and shows differential regulation under stress conditions. PMID:19222581,  Aravindhan V, Christy AJ, Roy S, Ajitkumar P, Narayanan PR, Narayanan S.,  FEMS Microbiol Lett.,  292(1),  (2009 Mar),  42-9, 
  • Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: Implications for vaccines. PMID:18845682,  Zhu Q, Egelston C, Vivekanandhan A, Uematsu S, Akira S, Klinman DM, Belyakov IM, Berzofsky JA.,  Proc Natl Acad Sci U S A.,  105(42),  (2008 Oct 9.),  16260–16265, 
  • Identification & differentiation of Mycobacterium avium & M. intracellulare by PCR- RFLP assay using the groES gene. PMID:18219086,  Aravindhan V, Sulochana S, Narayanan S, Paramasivam CN, Narayanan PR.,  Indian J Med Res.,  126(6),  (2007 Dec),  575-9, 
  • T-h-2 immunity and CD3+CD45RBlow-activated T cells in mice immunized with recombinant bacillus Calmette-Guérin expressing HIV-1 principal neutralizing determinant epitope. PMID:16706787,  Aravindhan V, Narayanan S, Gautham N, Prasad V, Kannan P, Jacobs WR Jr, Narayanan P.,  FEMS Immunol Med Microbiol.,  47(1),  (2006 Jun),  45-55, 
  • In-vivo study on “Dual Signal Hypothesis” & its correlation to humoral immune response using mycobacterial antigen.,  Aravindhan V. and Sulochana Das.,  Current Science,  81(3),  (2001 Aug),  301-304, 
  •   Increased Levels of Endotoxin Core Antibodies and Decreased Levels of sCD 14 Indicate Chronic Endotoxemia in Coronary Artery Disease (CURES-127).,  Aravindhan V.*, Mohan V, Madhumitha H, Valarmathi S, Babu S,  J Clin Exp Cardiolog,  4,  (2013 July),  264, 

Projects (Total Projects : 6)

Title:Role of Toll-Like Receptors (TLRs) in Diabetes and Tuberculosis (DM-TB) nexus (DST-FAST TRACK) SRF/FT/LS-105-2009    

Duration:3
Funded by:DST

Funded Amount (in Lakhs.):16

Title:Role of CD4+ T-Helper (Th) cells in Diabetes - Tuberculosis (DM-TB) Nexus 2012/37B/11/BRNS  

Duration:3
Funded by:DAE

Funded Amount (in Lakhs.):23

Title:Screening for latent and active TB and impaired Mtb specific immune responses among Type-2 Diabetic subjects in the Chennai based clinic population 

Duration:3
Funded by:DBT

Funded Amount (in Lakhs.):48

Title:Prediction of Treatment Failure among Diabetic Patients with Tuberculosis by Peripheral Blood Transcriptional Signature 

Duration:3
Funded by:DBT

Funded Amount (in Lakhs.):40

Title:TLR induced secretion of α-defensin in type-2- diabetic subjects

Duration:3
Funded by:Tamil Nadu State Research C

Funded Amount (in Lakhs.):1

Title:Role of Genetic Polymorphisms in determining Th1-Th2 responses in Diabetes-Latent Tuberculosis (DM-LTB) Nexus

Duration:3
Funded by:ICMR

Funded Amount (in Lakhs.):60

Awarded Scholars
No data available
Present Scholars
No data available

Post Doctoral Scholars (0)

No data available
Seminars / Conference
  • National
  • Internationals
Organised

Organized 4th Prof G Jayaraman Endoment national work shop and conference on recent trends in genomics and proteomics: Impact on human health, At the Dept of Genetics,University of Madras.

Held On2016
Participated

Invited lecture at knowledge sharing forum, Sci – Gate on 30th May, 2013(Thursday) between 3.00pm to 4.00pm at ORCHID Research and Development Centre, Sholinganallur, Chennai.

Held On2013

Invited talk in National Conference on Current Research Perspectives in Biotechnology, Heathcare and Environment organized by Dept. of Biotechnology, Dr. M.G.R Educational & Research Institute Maduravoyal, Chennai - 600095. April 15th- 16th 2013.

Held On2013

Invited speaker at Immuno-bites 2013 on 19th June 2013 at Dept of oral&maxillofacial pathology SRM Dental college and hospital, Ramapuram, Chennai-89.

Held On2013

Invited speaker at “VICENNIAL CELEBRATIONS” on 6 Feb  2014 at Post Graduate and Research Department of Biochemistry, Mohammad Sadak College of Arts and Science, Sholinganallur, Chennai-119  

Held On2014
Organised

Organized 12th Young Investigators Meeting  along with IISc, IITM and IBS

Held On2020

Skill Based Internship Program on IMMUNOGENETICS

Held On2021
Participated

Invited key note speaker at 9th International science and maths symposium at California State University, Fullerton, USA (Mar 20th 2013). 

Held On2013
Other Informations
  • Invited Talks
  • Patents
  • Additional Informations
Date Topic Venue
20/03/2013 Extended Hygiene Hypothesis Invited key note speaker at 9th International science and maths symposium at California State University Fullerton, USA (Mar 20th 2013).
A simple blood diagnostic test to detect pre-gestational diabetes in the first trimester of pregnancy

      A simple blood diagnostic test to detect pre-gestational diabetes in the first trimester of pregnancy

     (Application No: 202241001515) published on 11/01/2022

Read More

Additional Informations

SCHOLARSHIP/FELLOWSHIP

  1. DST-DAAD Indo german visiting fellowship- Visitig Scientist at UKSH, Kiel, Germany (2017-2019)
  2. Visiting scientist at AIDS International Training & Research Programe (AITRP) at Albert Einstein College of Medicine, Yeshiva University, New York.
  3. Visiting Scientist at Seattle Biomedical Research Institute under Global Infectious Diseases Fellowship.  
  4. Oak Ridge Institute for Science and Education (ORISE) Fellowship- visiting researcher at NIH
  5. NET-UGC-CSIR Junior Research Fellowship (JRF) was awarded for clearing the National Level Eligibility Test Conducted by UGC-CSIR research Organizations.
  6. GATE Junior Research Fellowship (JRF) was offered for clearing the National Level Graduate aptitude test for Engineering (Life Sciences).
  7. University first at MSc Biomedical genetics (1999 University of Madras)
  8. Dr.Sanjeeva raj Memorial Book Grant Scholarship was awarded at Madras Christian College for academic performance in B.Sc.
INDUSTRIAL CONSULTANCY

1. Project title "Estimation serum anti-Vi antibody titers in children vaccinated with typhoid vaccine (Peda Typh)"- Dr.Balaji Chinnasamy, Department of Pediatrics, SRM Medical College Hospital & Research Centre, SRM Nagar, Potheri Village, Kattankulathur-603203 & M/s Bio-Med Private Limited, Ghaziabad-201009, U.P.

DST-DAAD Visiting Scientist

 Indo-German colloboration with University of Kiel, Dept of Cardiology,  Kiel, Germany

Visiting Scientist AITRP

Indo-US colloboration with Prof William Jr Jacobs and Prof Vinayak K. Prasad at Albert Einstein College of Medicine, Yeshiva University, Bronx, NY, USA under Fogarty AIDS International Training and Research Program (AITRP) 

Visiting Scientist GID

Indo-US collobotation with Prof Kevin Urdahl,Seattle BioMed under Global Infectious Disease Research Training (GID) 

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